Keywords
ROS-1 positive NSCLC, Crizotinib, Lazarus response, Pulmonary embolism, Anticoagulant
Abstract
A 57-year-old woman with a ROS1-rearranged NSCLC patient demonstrated a Lazarus response to crizotinib but later developed recurrent pulmonary embolism (PE) with right ventricular (RV) failure. This incident highlights the potential crizotinib-related thrombotic risk and the need for appropriate monitoring of vascular complications, particularly in limited-option settings such as Thailand.
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Recommended Citation
Patrathiranond, Piraya; Thitvirachawat, Sasipim; and Eiamprapaporn, Panuch.
2026
Rapid Response, Unexpected Risk: A ROS1-Positive Non-Small Cell Lung Cancer (NSCLC) Case with Lazarus Syndrome and Fatal Thrombosis.
Asian Medical Journal and Alternative Medicine. 26,
1 (Jan. 2026 ), 56-59.
Available at: https://doi.org/10.70933/2773-9465.1331
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